Genes and Biology An individual's physiology is defined by the interactions
Genes and Biology
An individual’s physiology is defined by the interactions of their genetic and biological make-up with a multitude of external factors. The goal of this research focus area is to define the early life genetic and biological factors that contribute to life-long health and disease outcomes and develop interventions and therapies that can ameliorate or prevent disease.
The physical environment, including chemical agents, climate change, nanoparticles, microbes, endocrine disrupptors, and epigenetic modifiers, has a profound impact at all levels of physiology. The goal of this research focus area is to identify environmental factors that contribute to life-long health and disease outcomes and develop interventions and therapies to improve population health.
Health and Behavior Needs
From the prenatal period through the first few years of life, the brain undergoes it’s greatest period of development. Early life experiences are critical in developing a brain architecture that affects behavior, relationships, learning, and mental health over a lifetime. Elucidation of early life influences that contribute to emotional and behavioral health will aid in the development of interventions to improve mental and physical health outcomes.
Social and Economic Factors
Social and economic factors including occupation, education, income, family structure, community support, the emotional and physical health of those who live closest to us, and local resources influence all aspects of health, and these factors are particularly influential at early ages. Assessment of the social and economic factors that have lifelong impacts will identify policies and initiatives that can improve the health of all communities.
- Children’s Health & Discovery Initiative – Duke Department of Pediatrics
Sallie Permar is a Professor of Pediatrics in the Duke Department of Pediatrics.
Where to meet:
Selected attendees will be notified via email several days in advance of the dinner with details regarding meeting location. All dinners will be within reasonable driving distance to Duke campus.
Science & Society will also provide a shuttle for those unable to arrange transportation to the dinner dialogue location. Shuttles will depart 30 minutes before the scheduled event from the front entrance of the North Building on West Campus. Click here for a map.
(Monday) 7:00 pm - 8:30 pm
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