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Tue, May 10
Human-Derived Antibody Appears to Destroy Cancer Cells
Scientists at Duke University have developed an antibody that targets cancer cells and triggers an immune response to kill tumors while leaving other cells unharmed. The emerging approach to cancer treatment holds promise as an alternative to existing immunotherapies that pose unwanted side effects, researchers said.
The paper, published Thursday in Cell Reports, is the latest in a series of studies by the team, whose earlier research suggested the antibody helped halt progression of early-stage lung cancer. In subsequent research, they observed that a human-derived, purified antibody kills tumor cells when bound to a specific target, a protein called complement factor H (CFH), which protects cells from an immune system attack.